Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
John Leach0
James F. Martin0
Todd Ryan Heallen0
Yuka Morikawa0
Date of Patent
November 6, 2018
0Patent Application Number
156422000
Date Filed
July 5, 2017
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
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