Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Todd Ryan Heallen0
John Leach0
James F. Martin0
Yuka Morikawa0
Date of Patent
May 14, 2024
0Patent Application Number
179312700
Date Filed
September 12, 2022
0Patent Citations
Patent Primary Examiner
Patent abstract
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
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