Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
John Leach0
Yuka Morikawa0
Todd Ryan Heallen0
James F. Martin0
Date of Patent
October 4, 2022
0Patent Application Number
170962600
Date Filed
November 12, 2020
0Patent Citations Received
Patent Primary Examiner
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
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