US Patent 11459565 Hippo and dystrophin complex signaling in cardiomyocyte renewal
Patent 11459565 was granted and assigned to Baylor College of Medicine on October, 2022 by the United States Patent and Trademark Office.
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Patent Inventor Names
James F. Martin0
John Leach0
Todd Ryan Heallen0
Yuka Morikawa0
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US Patent 11459565 Hippo and dystrophin complex signaling in cardiomyocyte renewal
Article
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
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Current Assignee
Patent Jurisdiction
Patent Number
114595650
Date of Patent
October 4, 2022
0Patent Application Number
170962600
Date Filed
November 12, 2020
0Patent Citations
Patent Primary Examiner
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