Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
March 8, 2022
Patent Application Number
14781069
Date Filed
April 2, 2014
Patent Citations
...
Patent Citations Received
Patent Primary Examiner
Patent abstract
A polypeptide containing an antibody Fc region variant which has an amino acid sequence in which an amino acid alteration at position 238 according to EU numbering is combined with other specific amino acid alteration(s), was found to have decreased binding activities to all activating FcγRs, in particular FcγRIIa (R type), while maintaining its FcγRIIb-binding activity, when compared to a polypeptide containing a native IgG Fc region.
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