US Patent 11370825 Polypeptides, cells, and methods involving engineered CD16
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Edits on 23 Apr, 2023
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Patent Number
113708250
Date of Patent
June 28, 2022
0Patent Application Number
172339790
Date Filed
April 19, 2021
0Patent Primary Examiner
Edits on 29 Mar, 2023
Golden AI
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Edits on 23 Sep, 2022
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Patent Jurisdiction
Patent Number
113708250
Date of Patent
June 28, 2022
0Patent Application Number
172339790
Date Filed
April 19, 2021
0Patent Primary Examiner
Golden AI
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Edits on 29 Jun, 2022
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US Patent 11370825 Polypeptides, cells, and methods involving engineered CD16
Article
This disclosure describes, generally, a modified form of CD16, genetically-modified cells that express the modified CD16, and methods that involve the genetically-modified cells. The modified form of CD16 can exhibit increased anti-tumor and/or anti-viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.
Infobox
Is a
Patent jurisdiction
Patent number
11370825
Date of patent
June 28, 2022
Patent application number
17233979
Date Filed
April 19, 2021
Patent primary examiner
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