US Patent 11643446 Progranulin variants
Patent 11643446 was granted and assigned to Denali Therapeutics on May, 2023 by the United States Patent and Trademark Office.
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Patent Inventor Names
Ankita Srivastava0
Gerald Maxwell Cherf0
Gunasekaran Kannan0
Katrina W. Lexa0
Rachel Prorok0
Ray L. Y. Low0
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US Patent 11643446 Progranulin variants
Article
Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (e.g., a neurodegenerative disease, such as frontotemporal dementia (FTD)) are also provided herein.
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Patent Applicant
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Patent Jurisdiction
Patent Number
116434460
Date of Patent
May 9, 2023
0Patent Application Number
176977710
Date Filed
March 17, 2022
0Patent Citations
Patent Primary Examiner
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