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US Patent 11859179 Methods of treating amyotrophic lateral sclerosis (ALS)

Patent 11859179 was granted and assigned to University of Massachusetts on January, 2024 by the United States Patent and Trademark Office.

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 US Patent 11859179 Methods of treating amyotrophic lateral sclerosis (ALS)

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Patent abstract

Aspects of the disclosure relate to recombinant gene editing complexes comprising a recombinant gene editing protein and guide RNA (gRNA) that specifically hybridizes to a region of a C90RF72 gene (e.g., a region flanking a G

Infobox
Is a
Patent
Patent
0
Patent Applicant
University of Massachusetts
University of Massachusetts
0
Current Assignee
University of Massachusetts
University of Massachusetts
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118591790
Patent Inventor Names
Abbas Abdallah0
Christian Mueller0
Date of Patent
January 2, 2024
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Patent Application Number
166115810
Date Filed
May 9, 2018
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Patent Citations
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US Patent 7902163 Antisense modulation of superoxide dismutase 1, soluble expression
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US Patent 9284357 AAV's and uses thereof
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US Patent 9596835 Isolation of novel AAV's and uses thereof
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US Patent 10077452 rAAV-based compositions and methods
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US Patent 6953690 Compositions and methods for helper-free production of recombinant adeno-associated viruses
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Patent Primary Examiner
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Catherine S Hibbert
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CPC Code
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C12N 2310/20
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C12N 15/907
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C12N 15/86
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C12N 15/11
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C12N 2750/14171
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C12N 2750/14143
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C12N 2800/80
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C12N 9/22
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A61K 35/76
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