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US Patent 11873490 Antisense oligomers for treatment of conditions and diseases

Patent 11873490 was granted and assigned to Stoke Therapeutics on January, 2024 by the United States Patent and Trademark Office.

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 US Patent 11873490 Antisense oligomers for treatment of conditions and diseases

Article

Patent abstract

Alternative splicing events in SCN1A gene can lead to non-productive mRNA transcripts which in turn can lead to aberrant protein expression, and therapeutic agents which can target the alternative splicing events in SCN1A gene can modulate the expression level of functional proteins in Dravet Syndrome patients and/or inhibit aberrant protein expression. Such therapeutic agents can be used to treat a condition caused by SCN1A, SCN8A or SCN5A protein deficiency.

Infobox
Is a
Patent
Patent
0
Patent Applicant
Stoke Therapeutics
Stoke Therapeutics
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Current Assignee
Stoke Therapeutics
Stoke Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118734900
Patent Inventor Names
Isabel Aznarez0
Zhou Han0
Date of Patent
January 16, 2024
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Patent Application Number
171275810
Date Filed
December 18, 2020
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Patent Citations
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Patent Primary Examiner
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J. E. Angell
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CPC Code
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C12N 15/113
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A61K 9/0019
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A61P 25/12
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