US Patent 11884944 Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof
Patent 11884944 was granted and assigned to Denali Therapeutics on January, 2024 by the United States Patent and Trademark Office.
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US Patent 11884944 Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof
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Patent abstract
Provided herein are proteins, which are capable of being transported across the blood-brain barrier (BBB) and comprise sulfoglucosamine sulfohydrolase (SGSH) enzyme-Fc fusion polypeptides. Certain embodiments also provide methods of using such proteins to treat Sanfilippo syndrome A.
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Cathal S. Mahon0
Gunasekaran Kannan0
Mihalis S. Kariolis0
Tina Giese0
Date of Patent
January 30, 2024
0Patent Application Number
178555430
Date Filed
June 30, 2022
0Patent Citations
Patent Primary Examiner
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