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US Patent 12023331 Methods

Patent 12023331 was granted and assigned to Intra-Cellular Therapies on July, 2024 by the United States Patent and Trademark Office.

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 US Patent 12023331 Methods

Article

Patent abstract

The disclosure provides methods for the acute treatment of depression and/or anxiety, for the enhancement of mTOR (e.g., mTORC1) signaling, and for the reduction of neuroinflammation, comprising administering to a patient in need thereof, a therapeutically effective amount of a 5-HT

Infobox
Is a
Patent
Patent
0
Patent Applicant
Intra-Cellular Therapies
Intra-Cellular Therapies
0
Current Assignee
Intra-Cellular Therapies
Intra-Cellular Therapies
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120233310
Patent Inventor Names
Gretchen Snyder0
Lawrence P. Wennogle0
Robert Davis0
Date of Patent
July 2, 2024
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Patent Application Number
171154160
Date Filed
December 8, 2020
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Patent Citations
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US Patent 11124514 Compositions and methods
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US Patent 11096944 Organic compounds
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US Patent 7183282 Substituted heterocycle fused γ-carbolines
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US Patent 7223879 Ligands for metals and improved metal-catalyzed processes based thereon
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US Patent RE39679 Substituted heterocycle fused gamma-carbolines
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US Patent RE39680 Substituted heterocycle fused gamma-carbolines
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US Patent 7238690 Substituted heterocycle fused gamma-carbolines
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US Patent 7247731 Ligands for metals and improved metal-catalyzed processes based thereon
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US Patent 7323608 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds
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US Patent 7375226 Bi- and tricyclic substituted phenyl methanones
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US Patent 7462641 (2S,4S)-4-fluoro-1-[4-fluoro-beta-(4-fluorophenyl)-L-phenylalanyl]-2-pyrrolidinecarbonitrile
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US Patent 7592454 Substituted hexahydro-pyridoindole derivatives as serotonin receptor agonists and antagonists
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US Patent 7614727 Liquid ejection head, manufacturing method thereof, and image forming apparatus
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US Patent 7645752 Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors
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US Patent 7998971 Combinations containing a 4-acylaminopyridine derivative
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US Patent 8309722 Substituted heterocycle gamma-carbolines synthesis
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US Patent 8309772 Tunable catalyst gas phase hydrogenation of carboxylic acids
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US Patent 8461148 Use of memantine (namenda) to treat autism, compulsivity and impulsivity
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US Patent 8648077 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-fluorophenyl)-1-butanone toluenesulfonic acid addition salt and salt crystals
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US Patent 8779139 Substituted 2,3,4,4A,5,9B-hexahydro-1H-pyrido[4,3-B]indole derivatives synthesis and uses thereof
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US Patent 8791138 Compositions and methods for alleviating depression or improving cognition
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US Patent 8993572 Pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines derivatives and [1,4]oxazino[2,3,4-hi]pyrido[4,3-b]indole derivatives
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US Patent 9168258 Methods and compositions for sleep disorders and other disorders
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US Patent 9199995 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-fluorophenyl)-1-butanone toluenesulfonic acid addition salt and salt crystals
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US Patent 9315504 Preparation of 4-((6BR,10AS)-3-methyl-2,3,6B,9,10, 10A-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalin-8-(7H)-yl)-1-(4-fluorophenyl)-1-butanone or a pharmaceutically acceptable salt thereof
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US Patent 9371324 Substituted pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines for the treatment of nervous system disorders
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US Patent 9428506 Substituted pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines for the treatment of nervous system disorders
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US Patent 9586960 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de] quinoxalin-8(7H)-yl)-1-(4-fluorophenyl)-1-butanone toluenesulfonic acid salt crystal forms
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US Patent 9616061 Methods and compositions for sleep disorders and other disorders
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US Patent 9708322 Substituted pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalines for inhibiting serotonin reuptake transporter activity
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US Patent 9745300 Organic compounds
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US Patent 9751883 Preparation of certain [((6BR,10AS)-2,3,6B,7,8,9,10, 10A-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof
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US Patent 9956227 Method for the treatment of residual symptoms of schizophrenia
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US Patent 10072010 Substituted pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines for inhibiting serotonin reuptake transporter activity
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US Patent 10077267 Organic compounds
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US Patent 10117867 Methods and compositions for sleep disorders and other disorders
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US Patent 10179776 Compounds and methods of use to treat schizophrenia
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US Patent 10245260 Organic compounds
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US Patent 10322134 Methods
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US Patent 10472359 Pharmaceutical compositions comprising 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)-1-(4-fluorophenyl) butan-1-one for inhibiting serotonin reuptake transporter activity
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US Patent 10533015 Opioid receptor antagonist prodrugs
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US Patent 10597394 Organic compounds
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US Patent 10654854 Salts and crystals of ITI-007
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US Patent 10682354 Compositions and methods
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US Patent 10688097 Organic compounds
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US Patent 10702522 Methods and compositions for sleep disorders and other disorders
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US Patent 10716786 Transmucosal and subcutaneous compositions
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US Patent 10799500 Organic compounds
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US Patent 10844061 Pharmaceutical compositions comprising 4-(6BR,10AS)-3-methyl-2,3,6B,9,10,10A-hexahydro-1h, 7H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)-1-(4-fluorophenyl)butan-1-one and methods of treating conditions of the central nervous system
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US Patent 10899762 Organic compounds
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US Patent 10906906 Organic compounds
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US Patent 10960009 Methods of treating schizophrenia and depression
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US Patent 10960010 Pharmaceutical compositions for sustained or delayed release
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US Patent 10961245 Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
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US Patent 11014925 Co-crystals of 1-(4-fluoro-phenyl)-4-((6bR,1OaS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H- pyrido[3′,4′:4,51_pyrrolo [1,2,3-delqcuinoxalin-8-yl)-butan-1-one with nicotinamide or isonicotinamide
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US Patent 11026951 Methods of treating bipolar disorder
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US Patent 11052083 Transmucosal methods for treating psychiatric and neurological conditions
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US Patent 11053245 Methods
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US Patent 11376249 Organic compounds
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US Patent 6849619 Substituted pyridoindoles as serotonin agonists and antagonists
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US Patent 6849640 Therapeutic 1H-pyrido [4,3-b] indoles
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US Patent 6867298 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds
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US Patent 6888032 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds
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US Patent 6946560 Ligands for metals and improved metal-catalyzed processes based thereon
0
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US Patent 7026498 Ligands for metals and improved metal-catalyzed processes based thereon
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US Patent 7071186 Substituted heterocycle fused gamma-carbolines
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US Patent 7081455 Substituted heterocycle fused gamma-carbolines
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Patent Primary Examiner
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Sahar Javanmard
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CPC Code
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A61P 25/24
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A61P 25/22
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A61K 31/519
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A61K 31/4985
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