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US Patent 12103944 Compositions and methods for synthesizing 5′-capped RNAs

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Anton P. McCaffrey0

Richard I. Hogrefe0

Alexandre Lebedev0

Dongwon Shin0

Date of Patent

October 1, 2024

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Patent Application Number

184084310

Date Filed

January 9, 2024

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Patent Citations

US Patent 8344118 Preparation and isolation of 5′ capped MRNA

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US Patent 10487105 Trinucleotide MRNA cap analogs

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US Patent 10494399 Compositions and methods for synthesizing 5′-Capped RNAS

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US Patent 10519189 Compositions and methods for synthesizing 5′-Capped RNAs

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US Patent 10676499 3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA

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US Patent 10913768 Compositions and methods for synthesizing 5′-capped RNAs

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US Patent 11072808 Methods and compositions for increasing capping efficiency of transcribed RNA

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US Patent 11414453 Compositions and methods for synthesizing 5′-capped RNAs

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Patent Primary Examiner

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CPC Code

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Patent abstract

Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form

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