Techniques and apparatus for optimizing transmitter equalization are described. An example technique includes capturing a single output signal transmitted from a port on at least one channel of a host device. An impulse response of the channel is determined based at least in part on the single output signal. A transmitter feedforward equalization (FFE) is generated, based at least in part on the impulse response of the channel. The transmitter FFE is applied to the channel of the port of the host device.