Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Clark Q. Pan0
Baisong Mei0
Deqian Wang0
Hendri Tjandra0
Jianmin Chen0
John E. Murphy0
Jonathan S. Strauss0
Liang Tang0
...
Date of Patent
December 15, 2009
0Patent Application Number
112738960
Date Filed
November 14, 2005
0Patent Citations Received
Patent Primary Examiner
Patent abstract
This invention relates to Factor VIII muteins that are covalently bound, at one or more predefined sites that are not an N-terminal amine, to one or more biocompatible polymers such as polyethylene glycol. The mutein conjugates retain FVIII procoagulant activity, are capable of correcting human factor VIII deficiencies and have improved pharmacokinetic properties.
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