Patent 8940289 was granted and assigned to Altor BioScience on January, 2015 by the United States Patent and Trademark Office.
The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making such proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.