Patent 9464127 was granted and assigned to Altor BioScience on October, 2016 by the United States Patent and Trademark Office.
The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the such proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.