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US Patent 12104156 Compositions and methods of treating facioscapulohumeral muscular dystrophy

Patent 12104156 was granted and assigned to Avidity Biosciences on October, 2024 by the United States Patent and Trademark Office.

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 US Patent 12104156 Compositions and methods of treating facioscapulohumeral muscular dystrophy

Article

Patent abstract

Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.

Infobox
Is a
Patent
Patent
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Patent Applicant
Avidity Biosciences
Avidity Biosciences
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Current Assignee
Avidity Biosciences
Avidity Biosciences
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
121041560
Patent Inventor Names
Barbora Malecova0
Beatrice Diana Darimont0
David Sala Cano0
Rob Burke0
Date of Patent
October 1, 2024
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Patent Application Number
180528990
Date Filed
November 4, 2022
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Patent Citations
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US Patent 8618277 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
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US Patent 8632997 RNA sequence-specific mediators of RNA interference
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US Patent 8633185 Pyrrolobenzodiazepines
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US Patent 8648185 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
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US Patent 8778902 RNA interference mediating small RNA molecules
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US Patent 8835402 Compound and method for treating myotonic dystrophy
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US Patent 8846875 Preparation and/or purification of oligonucleotide conjugates
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US Patent 8993745 RNA interference mediating small RNA molecules
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US Patent 9139828 Method for efficient exon (44) skipping in duchenne muscular dystrophy and associated means
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US Patent 9175286 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
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US Patent 9175289 Reduced size self-delivering RNAi compounds
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US Patent 9181551 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
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US Patent 9243252 Oligomers
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US Patent 9249416 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
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US Patent 9441229 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
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US Patent 9447415 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
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US Patent 9447417 Multiple exon skipping compositions for DMD
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US Patent 9499818 Methods and means for efficient skipping of at least one of the exons 51-53, 55, 57 and 59 of the human duchenne muscular dystrophy gene
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US Patent 9708406 Anti-transferrin receptor antibodies and methods of use
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US Patent 9765338 Modulation of dystrophia myotonica-protein kinase (DMPK) expression
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US Patent 9796974 Modified RNAi agents
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US Patent 9982257 Chiral control
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US Patent 10550188 Nucleic acid-polypeptide compositions and uses thereof
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US Patent 10612027 Modified double-stranded RNA agents
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US Patent 10787519 Nucleic acid-polypeptide compositions and uses thereof
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US Patent 10800848 Nucleic acid-polypeptide compositions and uses thereof
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US Patent 10865445 Methods for alleviating facioscapulohumeral dystrophy (FSHD) by N siRNA molecule inhibiting the expression of DUX4-FL
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US Patent 10881743 Compositions and methods of treating muscle atrophy and myotonic dystrophy
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US Patent 10913800 Anti-transferrin receptor antibodies and uses thereof
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US Patent 10994020 Nucleic acid-polypeptide compositions and methods of inducing exon skipping
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US Patent 11028179 Anti-transferrin receptor antibodies and uses thereof
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US Patent 11246941 Compositions and methods of treating muscle atrophy and myotonic dystrophy
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US Patent 11253607 Compositions and methods of treating muscle atrophy and myotonic dystrophy
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US Patent 11286305 Complex comprising anti-transferrin receptor antibody covalently linked to an oligonucleotide that targets DUX4 RNA
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US Patent 11504391 Modified RNA agents with reduced off-target effect
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US Patent 11525137 Compositions and methods of treating Facioscapulohumeral muscular dystrophy
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US Patent 11555190 Compositions and methods of treating Facioscapulohumeral muscular dystrophy
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US Patent 11638761 Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
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US Patent 6849272 Endosomolytic agents and cell delivery systems
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US Patent 6942972 Efficient synthesis of protein-oligonucleotide conjugates
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US Patent 7049311 Pyrrolbenzodiazepines
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US Patent 7056704 RNA interference mediating small RNA molecules
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US Patent 7067511 Pyrrolobenzodiazepines
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US Patent 7078196 RNA interference mediating small RNA molecules
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US Patent 11834510 Anti-transferrin receptor antibodies and uses thereof
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US Patent 11912779 Compositions and methods of treating facioscapulohumeral muscular dystrophy
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Patent Primary Examiner
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Kimberly Chong
0

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