US Patent 11459335 N/O-linked Degrons and Degronimers for protein degradation
Patent 11459335 was granted and assigned to C4 Therapeutics on October, 2022 by the United States Patent and Trademark Office.
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Patent Inventor Names
Andrew J. Phillips0
Chi-Li Chen0
Christopher G. Nasveschuk0
James A. Henderson0
Martin Duplessis0
Minsheng He0
Yanke Liang0
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US Patent 11459335 N/O-linked Degrons and Degronimers for protein degradation
Article
This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation. The invention also provides Degrons that can be used to treat disorders mediated by cereblon or an Ikaros family protein, and methods of use and compositions thereof as well as methods for their preparation.
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
114593350
Date of Patent
October 4, 2022
0Patent Application Number
167216500
Date Filed
December 19, 2019
0Patent Citations
Patent Primary Examiner
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