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US Patent 12006520 Evaluation and improvement of nuclease cleavage specificity

Patent 12006520 was granted and assigned to President and Fellows of Harvard College on June, 2024 by the United States Patent and Trademark Office.

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 US Patent 12006520 Evaluation and improvement of nuclease cleavage specificity

Article

Patent abstract

Engineered nucleases are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. This disclosure provides in vitro selection methods that interrogate 10

Infobox
Is a
Patent
Patent
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Patent Applicant
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President and Fellows of Harvard College
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Current Assignee
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President and Fellows of Harvard College
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120065200
Patent Inventor Names
David R. Liu0
John Paul Guilinger0
Vikram Pattanayak0
Date of Patent
June 11, 2024
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Patent Application Number
164417510
Date Filed
June 14, 2019
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Patent Primary Examiner
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Frank W. Lu
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